Chroma ATE announced that its fully automated, open-platform nucleic acid testing system, GenXplore q4800, has been validated in a peer-reviewed study published in Microbiology Spectrum, a journal of the American Society for Microbiology (ASM).
The study evaluated the analytical and clinical performance of GenXplore q4800 using third-party manual molecular diagnostic kits targeting sexually transmitted infections and respiratory viruses. Automated testing demonstrated high repeatability, reproducibility, and sensitivity, with acceptable contamination control.
For clinical validation, 120 urine specimens were tested for Neisseria gonorrhoeae and Chlamydia trachomatis. Compared with a semi-automated reference method, GenXplore q4800 achieved 100% positive percent agreement, 100% negative percent agreement, and a Cohen's kappa coefficient of 1.0, indicating perfect concordance. In addition, professional users reported high satisfaction with system usability and workflow design.
These findings confirm that GenXplore q4800 delivers reliable performance while offering the flexibility of an open platform, providing laboratories with a robust alternative to closed, proprietary systems.
About GenXplore q4800
GenXplore q4800 is an all-on-one qPCR-based system developed by Chroma ATE. Designed as an open platform, it supports the integration of third-party reagents and workflows, helping laboratories balance automation efficiency, operational flexibility, and long-term sustainability.
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Microbiology Spectrum (American Society for Microbiology)
Performance evaluation of GenXplore q4800: a novel open-platform automated nucleic acid testing system